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Asan Medical Center

Publications

Scientific research papers published in our lab.

The most recently published paper

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Fitness

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Highlighted Papers

Our major articles published in major journals

in translational medicine, cell biology, biochemistry

: Cell Press, Nature Publishing Groups, Science Journals

Research Articles

Equally contributed authors#, Corresponding Author*

2024

Lee WJ, Kim SJ, Ahn Y, Park J, Jin S, Jang J, Jeong J, Park M, Lee YS, Lee J*, Seo D*. From Homogeneity to Turing Pattern: Kinetically Controlled Self-Organization of Transmembrane Protein. Nano Lett. 2024 Jan 10

2024

Pickel L, Kim SJ, Hacibekiroglu S, Nagy A, Lee J*, Sung HK*. The Circadian Clock of Müller Glia Is Necessary for Retinal Homeostasis and Neuronal Survival. Am J Pathol. 2024 Aug 13

2024

Dinah C, Chang A, Lee J. What is Occluding Our Understanding of Retinal Vein Occlusion? Ophthalmology and Theraphy. 2024 Oct 10

2024

Han YE, Jo J, Kim HC, Lee J. Choroidal manifestations of non-ocular sarcoidosis: an enhanced depth imaging OCT study. BMC Ophthalmology. 2024 Apr 26;24(1):199.

2023

Lee JH, Han YE, Yang J, Kim HC, Lee J. Clinical manifestations and associated factors of uveitis in patients with pulmonary sarcoidosis: a case control study. Sci Rep. 2023 Dec 16;13(1):22380

2022

Choe J#, Kim SJ#, Kim JH, Baik MH*, Lee J*, Cho J*. Photodynamic treatment of acute vascular occlusion by using an iron–nitrosyl complex. Chem. 2023 March 15

Choi SU, Kim YJ, Lee JY, Lee J*, Yoon YH. Qualitative and quantitative evaluation of diabetic choroidopathy using ultra-widefield indocyanine green angiography. Sci Rep. 2023 Feb 13;13(1):2577

Lee, J, Kim, YJ, Lee, JY, Yoon YH, Kim JG. Predictive factors for microvascular recovery after treatments for diabetic retinopathy. BMC ophthalmology. 2023; 23, 34

Son Y, Kim SJ, Kim HY, Lee J, Kim JY. Mdm1 ablation results in retinal degeneration by defective intraflagellar transport of photoreceptor cells. Cell Death & Disease. 2022 Sep 28;13(9):833

Yang JM, Kim SJ, Park SY, Son W, Kim A, Lee J. Exosomal miR-184 in the aqueous humor of patients with central serous chorioretinopathy: a potential diagnostic and prognostic biomarker. Journal of Nanobiotechnology. 2023 21, 242.

Kim SJ, Lim JS, Park JH, Lee J. Molecular, cellular, and functional heterogeneity of retinal and choroidal endothelial cells. Investigative Ophthalmology & Visual Science. 2023;64(10):35.

Han YE, Jo J, Kim YJ, Lee J. Factors Affecting Intensive Aflibercept Treatment Response in Diabetic Macular Edema: A Real-World Study. Journal of Diabetes Research. 2023 Article ID 1485059

Lee J#, Seo EJ#, Yoon YH. Rhegmatogenous retinal detachment induces more severe macular capillary changes than central serous chorioretinopathy. Sci Rep. 2022 Apr 29;12(1):7018.

Lim JS#, Moon C#. Lee J. Subretinal fluid disturbs the retinal venous blood flow in central serous chorioretinopathy. Sci Rep. 2022 Mar 22;12(1):4903.

Lee J, Kim YN, Kim JG. Monthly Alternating Injections of Aflibercept and Bevacizumab for Neovascular Age-Related Macular Degeneration. J Clin Med. 2022 Mar 11;11(6):1543

2021

Park J, Cho KJ, Lee J. Retinal granular cell tumor: A case report. BMC ophthalmology. 2021 Dec 27;21(1):453

2020

Kim SJ, Kim S, Choi YA, DY Park, Lee J. Alpha-smooth muscle actin-positive perivascular cells in diabetic retina and choroid. International Journal of Molecular Sciences. 2020 Mar 20;21(6):2158

Kim S, Kim SJ, Choi YA, Yoon HJ, Kim A, Lee J. Retinal VEGFA maintains the ultrastructure and function of choriocapillaris by preserving the endothelial PLVAP. Biochem Biophys Res Commun. 2020 Jan 29;522(1):240-246

Son S, Cho M, Lee J. Crumbs proteins regulate layered retinal vascular development required for vision. Biochem Biophys Res Commun. 2020 Jan 22;521(4):939-946

Choi DK, Kim YK, Park SW, Lee H, Lee S, Kim SA, Kim SJ, Lee J, Kim W, Min SH, Yu JH.The histone lysine methyltransferase SETD8 regulates angiogenesis through HES-1 in human umbilical vein endothelial cells.Sci Rep 10, 12089 (2020).

Yang JM, Park CS, Kim SH, Noh TW, Kim JH, Park S, Lee J, Park JR, Yoo D, Jung HH, Takase H, Shima DT, Schwaninger M, Lee S, Kim IK, Lee J, Ji YS, Jon S, Oh WY, Kim P, Uemura A, Ju YS, Kim I. Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis.Circ Res. 2020 Mar 13;126(6):767-783.

2019

Cho SM, Lee J, Lee HB, Choi HJ, Ryu JE, Lee HJ, Park HK, Lee MJ, Lee J, Lee HJ, Kim HS, Lee JY, Son WC. Subretinal transplantation of human embryonic stem cell-derived retinal pigment epithelium (MA09-hRPE): A safety and tolerability evaluation in minipigs. Regulatory Toxicology and Pharmacology 2019 Apr 19;106:7-14

Park HS, Kim HZ, Park JS, Lee J, Lee SP, Kim H, Ahn CW, Nakaoka Y, Koh GY, Kang S. β-Cell-Derived Angiopoietin-1 Regulates Insulin Secretion and Glucose Homeostasis by Stabilizing the Islet Microenvironment. Diabetes. 2019 Apr;68(4):774-786.

Ock S, Park S, Lee J, Kim J. RANKL blockade suppresses pathological angiogenesis and vascular leakage in ischemic retinopathy. Biochem Biophys Res Commun. 2019 Aug 20;516(2):350-356

2018

Moon BG, Um T, Lee J, Yoon YH. Correlation between Deep Capillary Plexus Perfusion and Long-Term Photoreceptor Recovery after Diabetic Macular Edema Treatment. Ophthalmol Retina. 2018 Mar;2(3):235-243.

Noh D, Ryu G, Lee J. Sagong M. Impact of Early Anatomical and Functional Responses to Bevacizumab in Macular Edema Secondary to Branch Retinal Vein Occlusion. Ophthalmologica 2018;239(4):194-204

2017

Park DY, Lee J, Kim J, Kim K, Hong S, Han S, Kubota Y, Augustin H, Ding L, Kim JW, He Y, Adams RH, Koh GY. Plastic roles of pericytes in the blood–retinal barrier. Nature Communications 2017 May 16;8:15296

Moon BG, Cho AR, Lee J, Kim YJ, Lee JY, Kim JG, Yoon YH. Improved Visual Outcome and Low Recurrence with Early Treatment with Intravitreal Anti-Vascular Endothelial Growth Factor in Myopic Choroidal Neovascularization. Ophthalmologica 2017;237(3):128-138

2016

Lee J, Moon BG, Cho AR, Yoon YH. Optical Coherence Tomography Angiography of Diabetic Macular Edema and its Association with Anti-VEGF Treatment Response. Ophthalmology 2016 Nov;123(11):2368-2375

Lee J, Sagong M, Ultra-Widefield Retina Imaging: Principles of Technology and Clinical Applications. Review Journal of Retina 2016 1(1)1-8 (Best paper award)

Jung J#, Lee J#, Yu SN, Kim YK, Lee JY, Sung H, Kim MN, Kim SH, Lee SO, Choi SH, Woo JH, Lee JY, Kim YS, Chong YP. Ocular involvement of Staphylococcus aureus bacteremia: incidence and risk factors. Antimicrobial Agents and Chemotherapy 2016 Mar 25;60(4):2012-7.

Kim Y, Nam HJ, Lee J, Park DY, Kim C, Yu YS, Kim D, Park SW, Bhin J, Hwang D, Lee H, Koh GY, Baek SH. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis Nature Communications 2016 Jan 13;7:10347

2013
~2015

Kim BH, Lee J, Choi JS, Park DY, Song HY, Park TK, Cho CH, Ye SK, Joo CK, Koh GY, Kim TY. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. British Journal of Pharmacology 2015 Aug;172(15):3875-89

Lee J, Lee JY. Hydroxychloroquine Retinopathy. Review. Journal of Rheumatic Diseases 2015 Jun 22(3):140-145.

Park DY, Lee J, Park. DY, Park I, Choi D, Lee S, Song S, Hwang Y, Hong KY, Nakaoka Y, Makinen T, Kim P, Hong YK, Koh GY. Lymphatic regulator PROX1 determines Schlemm’s canal integrity and identity. Journal of Clinical Investigation 2014 Sep;124(9):3960-74.

Ghim J, Moon JS, Lee CS, Lee J, Song P, Lee A, Jang JH, Kim D, Yoon JH, Koh YJ, Chelakkot C, Kang BJ, Kim JM, Kim KL, Yang YR, Kim Y, Kim SH, Hwang D, Suh PG, Koh GY, Kong YY, Ryu SH. Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis Arteriosclerosis, Thrombosis, and Vascular Biology 2014 Aug;34(8):1697-703.

Lee J, Park. DY, Park DY, Park I, Chang W, Nakaoka Y, Komuro I, Yoo OJ, Koh KY. Angiopoietin-1 Suppresses Choroidal Neovascularization and Vascular Leakage. Investigative Ophthalmology and Visual Science 2014, Apr 7;55(4):2191-9

Kim C, Yang H, Fukushima Y, Saw PE, Lee J, Park JS, Park I, Jung J, Kataoka H, Lee D, Heo WD, Kim I, Jon S, Adams RH, Nishikawa S, Uemura A, Koh GY. Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption. Cancer Cell 2014 Jan 13;25(1):102-17.

Jang JY, Koh YJ, Lee SH, Lee J, Kim KH, Kim D, Koh GY, Yoo OJ. Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes. Blood 2013 Sep 26;122(13):2151-61.

Lee J, Kim KE, Choi DK, Jang JY, Jung JJ, Kiyonari H, Shioi G, Chang W, Suda T, Mochizuki N, Nakaoka Y, Komuro I, Yoo OJ, Koh GY. Angiopoietin‐1 Guides Directional Angiogenesis Through Integrin αvβ5 Signaling for Recovery of Ischemic Retinopathy. Science Translational Medicine 2013:203ra127 (Selected as Cover Story).

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